Acitrin

Prescription Oral Retinoid (Psoriasis)

Acitretin Capsules

Manufacturer: Sun Pharma

Description

Acitrin is Sun Pharma's branded acitretin — an oral retinoid specifically used for psoriasis (unlike isotretinoin which is for acne). It normalises keratinocyte differentiation and proliferation. Particularly effective for pustular and erythrodermic psoriasis and palmoplantar keratoderma.

Active Compounds

Acitretin

Active ingredient — oral retinoid for psoriasis

Concentration: 10mg / 25mg

Tretinoin is a first-generation retinoid derived from vitamin A. It is one of the most extensively s…

Indications

  • Pustular psoriasis
  • Erythrodermic psoriasis
  • Severe plaque psoriasis
  • Palmoplantar keratoderma
  • Lichen planus (severe)

Dosage

25–50mg daily. Start low and titrate based on response and tolerability.

Formulations

Capsule

Full Ingredient List

  • Acitretin
  • Microcrystalline Cellulose
  • Gelatin
  • Sodium Ascorbate
  • Maltodextrin
  • Ascorbyl Palmitate

Side Effects

  • Mucocutaneous dryness (lips, skin, eyes)
  • Hair loss (telogen effluvium)
  • Elevated triglycerides and LFTs
  • Skeletal hyperostosis (long-term)
  • Photosensitivity

Warnings

  • Pregnancy Category X — teratogenic
  • Women must avoid pregnancy for 3 YEARS after stopping (not 1 month like isotretinoin)
  • Do not consume alcohol (converts acitretin to etretinate with longer half-life)
  • Monitor lipids and liver function
  • Avoid vitamin A supplements

Related Conditions

Psoriasis Oral retinoid for pustular, erythrodermic, and severe plaque psoriasis