Retin-A

Prescription Topical Retinoid

Tretinoin Cream

Manufacturer: Valeant Pharmaceuticals

Description

Retin-A is the original branded tretinoin formulation and remains the gold standard topical retinoid for acne and photoaging. Available in cream, gel, and microsphere formulations.

Active Compounds

Tretinoin

Active ingredient

Concentration: 0.025% / 0.05% / 0.1%

Tretinoin is a first-generation retinoid derived from vitamin A. It is one of the most extensively s…

Indications

  • Acne vulgaris
  • Photoaging
  • Fine wrinkles
  • Hyperpigmentation

Dosage

Apply a pea-sized amount to clean, dry skin once daily at bedtime. Begin with lowest concentration and titrate upward as tolerated.

Formulations

CreamGelMicrosphere gel

Full Ingredient List

  • Tretinoin
  • Stearic Acid
  • Isopropyl Myristate
  • Polyoxyl 40 Stearate
  • Stearyl Alcohol
  • Xanthan Gum
  • Sorbic Acid
  • Butylated Hydroxytoluene

Side Effects

  • Retinoid dermatitis (erythema, peeling, dryness)
  • Photosensitivity
  • Initial acne flare (purging)
  • Burning or stinging

Warnings

  • Avoid sun exposure; use broad-spectrum SPF 30+
  • Pregnancy Category X — contraindicated in pregnancy
  • Avoid concurrent use with other irritating agents
  • Apply moisturiser if dryness occurs

Related Conditions

Acne Vulgaris Prescription tretinoin for moderate–severe comedonal acne Melasma Tretinoin for epidermal melanin dispersal Photoaging Prescription tretinoin — evidence-based anti-photoaging therapy