Tri-Luma Cream (Fluocinolone 0.01% + Hydroquinone 4% + Tretinoin 0.05%)
Galderma · International (available in India)
Price: ₹800–₹1800
Description
Tri-Luma is the original triple combination (modified Kligman formula) cream for melasma. Contains the most evidence-based concentrations of fluocinolone acetonide, hydroquinone, and tretinoin. Considered the gold standard for melasma treatment worldwide.
Active Compounds
Hydroquinone
Tyrosinase inhibitor — depigmenting
Concentration: 4%
Alpha arbutin is a biosynthetic glycosylated hydroquinone derivative that inhibits melanin productio…
Tretinoin
Retinoid — enhances drug penetration, cell turnover
Concentration: 0.05%
Tretinoin is a first-generation retinoid derived from vitamin A. It is one of the most extensively s…
Fluocinolone Acetonide
Corticosteroid — anti-inflammatory
Concentration: 0.01%
Hydrocortisone is a low-potency topical corticosteroid identical to endogenous cortisol. It is the m…
Full Ingredient List (INCI)
- Fluocinolone Acetonide
- Hydroquinone
- Tretinoin
- Butylated Hydroxytoluene
- Citric Acid
- Glycerin
- Glyceryl Stearate
- Magnesium Aluminum Silicate
- Methyl Gluceth-10
- Methylparaben
- PEG-100 Stearate
- Propylparaben
- Sodium Metabisulfite
- Stearic Acid
- Purified Water
Suitable Skin Types
Key Features
- Gold-standard triple combination for melasma
- Original modified Kligman formula
- 4% hydroquinone — highest concentration
- Fluocinolone — low-potency steroid for safety
- Strictly prescription-only
- Must not exceed 8 weeks of continuous use
Usage
Apply a thin layer to melasma patches once daily at bedtime, at least 30 minutes before sleep. Always use with strict sun protection. Do not exceed 8 weeks of use.